The CGRB Biocomputing and Bioinformatics facility provides wide-ranging resources, expertise and support for computational needs of the molecular biosciences community at Oregon State University. The facility offers a robust computing environment for high-level computational biology and a versatile intellectual resource for interdisciplinary collaboration.
Since 2001, the CGRB has focused investments towards a scalable and distributed infrastructure capable of supporting highly parallel computing. Based extensively on open-source technologies and the Linux operating system, the infrastructure includes servers that host websites, handle much of the molecular sequence database search load (BLAST, FASTA, HMMER), and function as the SQL database server on which much of our custom-designed software relies. To manage the ever-increasing amount of data generated by new technologies like the Illumina DNA sequencer, the infrastructure also includes nearly 100TB of shared disk space for storage and backup purposes. The CGRB leads a significant software development effort that allows researchers across campus to tap into the power of biocomputing.
The infrastructure also features "Genome", a 330-node Beowulf-style, Linux-based compute-farm. Nodes in Genome range from single-processor to multi-processor multi-core machines with over 32GB of RAM. The CGRB encourages faculty to contribute to the infrastructure by purchasing server-class machines and nodes in Genome. Faculty have priority access to their own machines, which also become integrated into the overall computational infrastrucuture. This agglomerative strategy allows bioscientists to accomplish computationally-intensive research with only moderate hardware investments.
In addition to developing a scaleable hardware infrastructure, the CGRB has grown significantly as an intellectual resource for computational biology at OSU. This represents a major attraction for new research faculty recruited to OSU, and offers a vehicle through which faculty can development their own tools and resources for computational biology at OSU.
CGRB Biocomputing Group
Shawn O'Neil provides bioinformatics education services, as well as consultation and networking services regarding bioinformatics techniques and research.
Matthew Peterson develops and maintains the CGRB Core Laboratories computational environment, which enables Core Labs and researchers to place orders, access data and monitor progress of jobs. With his experience in various programming languages, Matthew will increasingly be involved with biocomputing projects in the future.
Chris Sullivan serves as the CGRB systems administrator and has extensive expertise in all aspects of hardware and infrastructure design and maintenance. Chris also develops software and applications.